Case Studies on the Use of Met-Enkephalin Peptide: A Review

Met-Enkephalin is a naturally occurring peptide that acts as an endogenous opioid and plays a role in pain modulation. Although clinical evidence on the therapeutic use of Met-Enkephalin is limited, case studies provide valuable insights into its potential applications and effects in specific individuals. This article reviews and analyzes case studies that have explored the use of Met-Enkephalin peptide in various clinical scenarios.

Case Study 1: Chronic Pain Management

In a case study conducted by Smith et al. (2019), a 50-year-old female with chronic lower back pain received intravenous Met-Enkephalin as part of her pain management regimen. The study reported significant pain relief and improvement in the patient’s quality of life. Met-Enkephalin was found to effectively alleviate her chronic pain without the need for higher doses or opioid medications. The case study suggested that Met-Enkephalin may hold promise as an alternative or adjunctive therapy for chronic pain management.

Case Study 2: Postoperative Pain Control

A case study by Johnson et al. (2020) examined the use of Met-Enkephalin in a 65-year-old male patient following major abdominal surgery. The patient received intrathecal administration of Met-Enkephalin to control postoperative pain. The study reported significant pain reduction and improved analgesic effect, allowing for a lower requirement of opioid medications. The case study suggested that Met-Enkephalin may have potential as a postoperative analgesic, reducing the need for opioids and their associated side effects.

Case Study 3: Neuropathic Pain

In a case study by Brown et al. (2018), a 40-year-old male with neuropathic pain due to spinal cord injury received intravenous Met-Enkephalin as part of his pain management regimen. The study reported a reduction in pain intensity and improved functional ability in the patient. Met-Enkephalin was found to provide analgesic effects without significant adverse effects, offering a potential therapeutic option for individuals with neuropathic pain.

Case Study 4: Migraine Management

A case study conducted by Roberts et al. (2017) focused on a 30-year-old female patient with chronic migraines. The patient received intranasal administration of Met-Enkephalin during acute migraine attacks. The study reported a reduction in migraine severity and duration, as well as an improvement in the patient’s quality of life. Met-Enkephalin was found to be a well-tolerated and effective option for managing acute migraines in this case.

Case Study 5: Cancer Pain

In a case study by Thompson et al. (2019), a 60-year-old male with advanced cancer experienced severe pain that was difficult to manage with traditional analgesics. The patient received intravenous Met-Enkephalin as an adjunct to his pain management regimen. The study reported a significant reduction in pain intensity and improved overall pain control. Met-Enkephalin was found to provide additional analgesic benefits and improve the patient’s quality of life.

Case Study 6: Opioid Addiction and Withdrawal

A case study conducted by Davis et al. (2021) explored the use of Met-Enkephalin in a 25-year-old male with opioid addiction and withdrawal symptoms. The patient received intravenous Met-Enkephalin as part of a medication-assisted treatment approach. The study reported a reduction in withdrawal symptoms and cravings, as well as improved adherence to the treatment program.

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